Category: Articles and studies

The difference between Indonal Forte and Indonal Woman

The difference between Indonal Forte and Indonal Woman

Articles and studies

27. June 2024

Indonal Forte and Indonal Woman contain the same main active ingredient, Indole-3-Carbinol, and thus have similar therapeutic effects. However, Indonal Forte has a higher content of this main active ingredient, specifically 50 mg more per capsule, and also includes curcumin, which has chemopreventive effects (the ability of certain substances to prevent, delay, or reduce the risk of cancer), and piperine, which enhances the effectiveness and absorption of the active ingredients. Therefore, if you do not have an allergy to curcumin, we recommend choosing Indonal Forte. If you are taking Indonal preventively or have an allergy to curcumin, we recommend Indonal Woman.

View article
Studies

Studies

Articles and studies

14. March 2024

Dietary indole-3-carbinol (I3C) has clinical benefits for both cervical cancer and laryngeal papillomatosis, and causes apoptosis of breast cancer cells in vitro.

View article
Climacterium and Indonal FORTE® – first aid

Climacterium and Indonal FORTE® – first aid

Articles and studies

03. May 2022

The climacteric period can be depressing and complicated for many women. At the first symptoms and missed periods at this age, it is necessary to seek the help of a gynecologist who will assess the condition, carry out careful examinations and set up the correct treatment. The treatment is based on the supplementation of hormones, but the composition of the diet and the substance I3C are also excellent helpers during menopause. It has a beneficial effect on the hormonal balance of women and is especially beneficial during the menopause.

View article
Use of I3C in gynecology

Use of I3C in gynecology

Articles and studies

03. May 2022

Indole-3-carbinol is a phytochemical obtained from cruciferous plants. After its consumption, several oligomeric components with different biological effectiveness are formed, including 3,3'-diindolylmethane. They are characterized by anti-estrogenic and anti-proliferative activity. Studies have yielded positive results when investigating the effect of indole-3-carbinol in various oncological diseases, demonstrating beneficial changes in estrogen metabolism. The use of indole-3-carbinol is applied in the prevention and treatment of papillomatous diseases caused by human papillomavirus, as well as in endometrial cancer and early stages of breast cancer. By influencing estrogen metabolism, glucose metabolism, and reducing insulin resistance, it appears to be a promising adjunctive treatment in polycystic ovary syndrome. Indole-3-carbinol is considered safe even with long-term use.

View article
I3C and breast cancer

I3C and breast cancer

Articles and studies

03. May 2022

Recent research, including studies in labs and on people, shows that a substance called indole-3-carbinol may help prevent various cancers, including breast cancer. When taken by mouth, indole-3-carbinol can positively impact how our bodies handle estrogen. It changes the balance between two types of estrogen metabolites, where one type is linked to a higher risk of breast cancer, and the other is associated with a lower risk. This suggests that indole-3-carbinol could be a good option for clinical trials in women with an increased risk of breast cancer. Additionally, it seems to selectively target and stop the growth of breast cancer cells without affecting normal breast cells.

View article
I3C and cervical lesions

I3C and cervical lesions

Articles and studies

03. May 2022

The indole derivative, indole-3-carbinol (I3C), is a naturally occurring substance in cabbage plants. This substance inhibits cell proliferation, arrests the cell cycle in the G1 phase, and induces apoptosis, thereby suppressing tumorigenesis. Its use could thus help in the prevention and treatment of some diseases, including cervical lesions. However, the molecular mechanisms by which indoles suppress tumorigenesis are not precisely known. Women with cervical intraepithelial neoplasia II and III (CIN II/III) have a lower 2:16α-hydroxyestrone ratio compared to women with physiologic findings on the cervix. I3C effectively increases the 2-hydroxylation of estrogen in liver cells and promotes the formation of 2-hydroxyestrone at the expense of 16α-hydroxyestrone. I3C could, therefore, be used as an adjunct in the treatment of cervical lesions. However, its application is broader. Currently, several preparations and nutritional supplements containing indole-3-carbinol are available on the market. The recommended daily dose of I3C is 200-400 mg twice daily for...

View article
Dangerous Estrogen Dominance and I3C

Dangerous Estrogen Dominance and I3C

Articles and studies

03. May 2022

Dr. John Lee was the first to use the term: "estrogen dominance", and spent several years searching for the cause of women's problems such as PMS, endometriosis, ovarian cysts, fibroids, breast cancer, infertility, osteoporosis and menopause. Based on his clinical experience of women's health and also from published research, he came to the conclusion that the health problems of many women (but also men) are caused by the excess of estrogen present. Estrogen has three basic types: estradiol, estrone, and estriol. Estradiol controls female sexual development, promotes the growth and function of female genitalia and secondary female sex characteristics, and participates in bone mineral homeostasis.

View article
Healthy intimate life

Healthy intimate life

Articles and studies

03. May 2022

Indonal Man positively affects the metabolism of male sex hormones, benefiting the urinary and sexual systems, and provides revitalizing effects in addressing prostate problems. The inclusion of Saw Palmetto, a key component, supports the metabolism of healthy testosterone in the male body and promotes the well-being of the prostate and urogenital tract.

View article
Natural herbs for women’s health

Natural herbs for women’s health

Articles and studies

03. May 2022

Nature is a powerful sorceress, and INDONAL WOMAN®, a nutritional supplement containing the recommended daily dose of Indole-3-carbinol, draws its essence from her. Typically derived from natural extracts found in broccoli and other cruciferous vegetables (cabbage, kohlrabi, cauliflower), this supplement's unique herbal composition bestows significant benefits on women's health, particularly during menopause. It contributes to maintaining hormonal balance, aiding with tissue changes in hormone-dependent areas like the cervix, uterus, ovaries, and breasts. INDONAL WOMAN® serves as a testament to the harmonious blend of nature's wisdom and scientific innovation.

View article
INDONAL in the treatment of mastopathy

INDONAL in the treatment of mastopathy

Articles and studies

03. May 2022

We conducted a study on various diagnoses, with one of the aims being to determine the influence of breast tenderness using the recommended nutritional supplement Indonal. The study involved 27 doctors from all over Slovakia, and 316 women were included in the research. The preparation was evaluated over 6 months. Overall, 81% of women reported an improvement or even disappearance of pain, 15% did not feel any improvement, and 4% experienced a worsening of pain. Indonal can cause mild side effects in some cases. Among the most common were a feeling of increased breast pain in the mentioned 4% of women, bloating, a smaller amount of stomach nausea, and light bleeding outside the menstrual cycle. The results processed so far indicate a significant improvement in findings among women experiencing breast pain. In most patients, there was a reduction in cyclic and non-cyclic pain, along with an improvement in mastopathy when...

View article